维基百科中的醫學内容仅供参考，並不能視作專業意見。如需獲取醫療幫助或意見，请咨询专业人士。詳見醫學聲明。

benzhydrocodone/acetaminophen and diazepam equally increase sedation. Keep away from or Use Alternate Drug. Limit use to patients for whom different treatment method solutions are insufficient

buprenorphine transdermal and diazepam each improve sedation. Steer clear of or Use Alternate Drug. Limit use to clients for whom alternative therapy selections are inadequate

fentanyl transmucosal and diazepam both improve sedation. Stay clear of or Use Alternate Drug. Restrict use to clients for whom alternate cure possibilities are insufficient

danazol will raise the degree or impact of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.

quinupristin/dalfopristin will enhance the level or result of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.

Clients from the aforementioned groups are monitored extremely carefully all through therapy for signs of abuse and growth of dependence. Therapy is recommended to be discontinued if any of those symptoms are famous.

Check Closely (1)enasidenib will boost the degree or outcome of diazepam by affecting hepatic enzyme CYP2C19 metabolism.

Medicines that have stage therapy associated with Just about every prescription. This restriction typically requires that particular criteria be achieved previous to acceptance to the prescription.

Breastfeeding. Diazepam passes into breast milk. Explain to your healthcare service provider Should you be breastfeeding or intend to breastfeed. Your healthcare supplier will suggest you if it is best to use diazepam even though breastfeeding.

Coadministration of other CNS depressants or Liquor usage may well potentiate CNS-depressant consequences of diazepam

Keep track of Intently (1)ethinylestradiol will boost the stage or influence of diazepam by System: decreasing metabolism.

nifedipine will boost the level or influence of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.

Despite the fact that not normally lethal when taken on your own, a diazepam overdose is considered a professional medical unexpected emergency and usually calls click here for the instant attention of clinical personnel. The antidote for an overdose of diazepam (or almost every other benzodiazepine) is flumazenil (Anexate). This drug is barely Utilized in circumstances with intense respiratory despair or cardiovascular problems. Mainly because flumazenil is a brief-acting drug, and the consequences of diazepam can last for times, quite a few doses of flumazenil might be essential.